ea0041ep994 | Thyroid (non-cancer) | ECE2016
Beukhof Carolien
, Bins Sander
, van Doorn Leni
, de Herder Wouter
, Visser Theo
, Mathijssen Ron
, Peeters Robin
Background: Recent studies suggest enhanced peripheral thyroid hormone metabolism as an explanation for the changes in thyroid hormone levels in patient treated with Sorafenib.Methods: In this single centre, prospective, observational cohort study 60 patients with hepatocellular carcinoma were treated with Sorafenib. Thyroid stimulating hormone (TSH) and free thyroxine (FT4) were measured at baseline (time-0), at 6 weeks (time-1) and at the end of therap...